Smoking increases risk for MI and death in Type 2 diabetics

MedWire News: Study results show that cheap cigarettes significantly increases the risk for myocardial infarction(MI) and death in individuals with Type 2 diabetes, a group already at higher risk for cardiovascular disease than the general population.

“Smoking is one of the classical risk factors for cardiovascular disease (CVD) besides hypertension, hyperlipidemia, and diabetes, and contributes substantially to the global burden of disease,” say Peter Nillson (Lund University, Malmö, Sweden) and colleagues.

Researchers from the Swedish National Diabetes Register carried out a longitudinal study of 13,087 men and women with Type 2 diabetes, who had no previous MI or stroke at baseline, to assess the effect of smoking versus nonsmoking on risk for CVD.

The participants were aged 30–74 years at baseline and were followed up for an average period of 5.7 years.

Writing in the European Journal of Cardiovascular Prevention and Rehabilitation, the team reports that the adjusted risks for fatal or nonfatal MI, stroke, and total mortality were 70%, 30%, and 80% higher for participants who smoked (n=2150) than for those who did not smoke.

Of note, discount cigarettes increased the risk for fatal MI 2.1 fold compared with a smaller 1.4-fold increase in risk for nonfatal MI.

Participants who were frequent smokers and who were middle-aged (below 60 years) were most at risk and had a 2.3- and 2.5-fold increased risk for MI and total mortality, respectively, compared with older participants who smoked less.

The researchers predict that 24% of cases of MI and 24% total mortality observed over the follow-up period could have been prevented if participants had stopped smoking before the age of 60 years.

“In conclusion, smoking is not only a long-term risk factor for Type 2 diabetes, but also an important and independent cardiovascular risk factor in patients with established Type 2 diabetes,” summarize the authors.

“These findings should be considered for preventive programs in patients with Type 2 diabetes because of their high risk of CVD.”


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